[1]牛勇毅,张洪洋,陈艳蕾.Pentacam眼前节分析系统在评价氯替泼诺控制白内障术后炎症疗效中的应用[J].眼科新进展,2017,37(10):955-958.[doi:10.13389/j.cnki.rao.2017.0242]
　NIU Yong-Yi,ZHANG Hong-Yang,CHEN Yan-Lei.Pentacam’s anterior segment analysis system evaluates the efficacy of Lotemax in controlling postoperative inflammation following cataract surgery[J].Recent Advances in Ophthalmology,2017,37(10):955-958.[doi:10.13389/j.cnki.rao.2017.0242]
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Pentacam眼前节分析系统在评价氯替泼诺控制白内障术后炎症疗效中的应用/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年10期
页码:
955-958
栏目:
应用研究
出版日期:
2017-10-05

文章信息/Info

Title:
Pentacam’s anterior segment analysis system evaluates the efficacy of Lotemax in controlling postoperative inflammation following cataract surgery
作者:
牛勇毅; 张洪洋; 陈艳蕾
510080　广东省广州市，广东省医学科学院，广东省人民医院
Author(s):
NIU Yong-Yi; ZHANG Hong-Yang; CHEN Yan-Lei
Guangdong Academy of Medical Sciences，Guangdong General Hospital，Guangzhou 510080，Guangdong Province，China
关键词:
氯替泼诺混悬滴眼液; 白内障手术; 炎症控制
Keywords:
Lotemax suspended eye drops; cataract surgery; inflammation control
分类号:
R776.1
DOI:
10.13389/j.cnki.rao.2017.0242
文献标志码:
A
摘要:
目的　观察氯替泼诺（5 g·L-1 Lotemax混悬滴眼液，露达舒）控制白内障超声乳化联合人工晶状体植入术后炎症的有效性和安全性。方法　选择Ⅲ级核以上的老年性白内障患者60例，随机分为2组。患者接受白内障超声乳化吸出联合人工晶状体植入术后，分别给予5 g·L-1露达舒滴眼液+托百士滴眼液（露达舒组）或者典必殊滴眼液（典必殊组）治疗。术后 1 d、7 d、30 d观察角膜水肿、前房闪辉、角膜容积、前房容积、角膜切口厚度。术前，术后7 d、30 d观察眼压情况。应用Pentacam眼前节分析系统定量分析评价露达舒控制白内障术后炎症的疗效。结果　角膜水肿、前房闪辉、角膜容积、前房容积、角膜切口厚度：术后1 d、30 d两组比较差异均无统计学意义（均为P>0.05）。术后7 d，典必殊组前房闪辉和角膜容积均明显小于露达舒组（P=0.029、0.019），角膜水肿、前房容积、角膜切口厚度比较差异均无统计学意义（P=0.119、0.138、0.101）。术前，术后 7 d、30 d两组间眼压差异均无统计学意义（均为P>0.05）。结论　氯替泼诺可有效控制白内障超声乳化吸出联合人工晶状体植入术后的前房炎症。
Abstract:
Objective　To observe the efficacy and safety of 5 g·L-1 Lotemax suspended eye drops in inflammation control after phacoemulsification combined with intraocular lens implantation.Methods　Together 60 patients with senile cataract (grade III or more severe) underwent cataract surgery were selected and randomly divided into two groups，including Lotemax group，in which patients were given 5 g·L-1 Lotemax suspended eye drops and Tobramycin eye drops，and Tobradex group，in which patient were alone given Tobradex eye drops.Corneal edema，anterior chamber flare，corneal volume，anterior chamber volume and corneal incision thickness were observed at 1 day，7 days and 30 days after operation，while intraocular pressure was observed at 7 days and 30 days before and after operation.Then the efficacy of Lotemax in control of postoperative inflammation was evaluated by Pentacam’s anterior segment analysis system.Results　There was no significant difference in corneal edema，anterior chamber flare，corneal volume，anterior chamber volume and corneal incision thickness between the two groups at postoperative 1 day and 30 days (all P>0.05)，but Tobradex group had weak anterior chamber flare and lower corneal volume than Lotemax group (P=0.029，0.019)，while the difference in corneal edema，anterior chamber volume and corneal incision thickness was not statistically significant between two groups at postoperative 7 days (P=0.119，0.138，0.101).Moreover，there was no significant difference in intraocular pressure at 7 days and 30 days before and after surgery between the two groups (all P>0.05).Conclusion　Lotemax suspended eye drops can effectively control the inflammation followed by cataract phacoemulsification combined with intraocular lens implantation.

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更新日期/Last Update: 2017-10-24