[1]马颖,邵彦.1.8 mm小切口超声乳化劈核与常规切口超声乳化白内障吸出术后早期恢复中角膜内皮细胞的变化[J].眼科新进展,2017,37(7):643-646.[doi:10.13389/j.cnki.rao.2017.0163]
 MA Ying,SHAO Yan.Changes of corneal endothelial cells in early recovery period after 1.8 mm small-incision phacoemulsification nucleus chopping and conventional incision phacoemulsification for cataract[J].Recent Advances in Ophthalmology,2017,37(7):643-646.[doi:10.13389/j.cnki.rao.2017.0163]
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1.8 mm小切口超声乳化劈核与常规切口超声乳化白内障吸出术后早期恢复中角膜内皮细胞的变化/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年7期
页码:
643-646
栏目:
应用研究
出版日期:
2017-07-05

文章信息/Info

Title:
Changes of corneal endothelial cells in early recovery period after 1.8 mm small-incision phacoemulsification nucleus chopping and conventional incision phacoemulsification for cataract
作者:
马颖邵彦
116027 辽宁省大连市,大连医科大学附属第二医院眼科
Author(s):
MA YingSHAO Yan
Department of Ophthalmology,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,Liaoning Province,China
关键词:
白内障小切口超声乳化劈核技术角膜内皮细胞
Keywords:
cataractsmall incision phacoemulsificationnucleus choppingcorneal endothelial cells
分类号:
R776.1
DOI:
10.13389/j.cnki.rao.2017.0163
文献标志码:
A
摘要:
目的 比较1.8 mm小切口超声乳化劈核与常规切口超声乳化白内障吸出术治疗白内障术后早期恢复中角膜内皮细胞的变化特点。方法 根据不同术式将53例白内障患者分为观察组与对照组,观察组行1.8 mm小切口超声乳化劈核治疗,对照组则采取常规切口超声乳化白内障吸出术,分别于术前1 d,术后1 d、1周、4周测定并记录两组患者视力、散光程度、角膜内皮细胞指标及并发症发生情况。结果 观察组有效超声时间、平均超声能量均显著少于对照组(均为P<0.05);与术前1 d比较,两组术后1周、4周,视力、散光程度、角膜内皮细胞面积(corneal endothelial cell area,ECA)、变异系数(coefficient of variation,CV)均显著上升,角膜内皮细胞密度(corneal endothelial cell density,CD)显著下降,差异均有统计学意义(均为P<0.05);观察组术后1 d、1周、4周,视力、ECD水平均显著高于对照组,散光程度、ECA、CV均显著低于对照组,差异均有统计学意义(均为P<0.05);观察组术中、术后并发症发生率均显著低于对照组(均为P<0.05)。结论 超声乳化白内障吸出术后患者角膜内皮细胞多遭受不同程度的损伤,但相比传统切口超声乳化白内障手术,1.8 mm小切口超声乳化劈核治疗术对角膜内皮细胞的损伤明显减轻,且能明显缩短超声时间,减少超声能量,减轻患者术后散光程度,进而显著提高其术后视力,减少术后角膜水肿发生。
Abstract:
Objective To compare the changes of corneal endothelial cells in early recovery period after 1.8 mm small incision phacoemulsification nucleus chopping and conventional incision phacoemulsification for cataract.Methods Fifty-three patients with cataract were divided into the observation group and control group according to different operation methods.The observation group was treated with 1.8 mm small incision phacoemulsification nucleus chopping while the control group was treated with routine incision phacoemulsification.The visual acuity,degree of astigmatism,corneal endothelial cell indexes and complications were observed.Results The effective ultrasound time and average ultrasonic energy of the observation group were significantly less than those of the control group (all P<0.05).Compared with 1 day before operation,the visual acuity,degree of astigmatism,corneal endothelial cell area (ECA) and coefficient of variation (CV) were significantly increased at 1 week and 4 weeks after operation,and corneal endothelial cell density (ECD) was significantly decreased (all P<0.05).The visual acuity and ECD levels of the observation group at 1 day,1 week and 4 weeks after operation were significantly higher than those of the control group,while the degree of astigmatism,ECA and CV were significantly lower than those of the control group (all P<0.05).Conclusion Compared with the traditional incision phacoemulsification,the damage of 1.8 mm small incision phacoemulsification nucleus chopping to corneal endothelial cells is significantly milder,can reduce the effective ultrasound time and average ultrasonic energy,decrease the degree of astigmatism,improve the visual acuity and decrease the corneal edema.

参考文献/References:

[1] 陈冬斌,董万江,廖文勇,颜瑞.硬核白内障超声乳化手术中预劈核与拦截劈核技术的比较[J].中华眼视光学与视觉科学杂志,2016,18(7):433-435.
CHEN DB,DONG WJ,LIAO WY,YAN R.Comparison of pre-chop and stop-and-chop techniques in phacoemulsification of hard-nucleus cataract[J].Chin J Optomet Ophthalmol Vis Sci,2016,18(7):433-435.
[2] 金守梅,冯运红,谢静,陈兆升,曾婷.小切口劈核法与超声乳化白内障摘除术治疗老年性硬核性白内障的疗效比较[J].蚌埠医学院学报,2016,41(7):908-911.
JIN SM,FENG YH,XIE J,CHEN ZS,ZENG T.Comparison of therapeutic effect of small incision nucleus fragmentation method and phacoemulsification cataract surgery in the treatment of senile hard nuclear cataract[J].J Bengbu Med Coll,2016,41(7):908-911.
[3] 杨卫国,肖远亮,陈曦,曾圆圆,肖乐.小切口手法劈核非超声乳化白内障摘除术的疗效分析[J].西南国防医药,2012,22(3):281-282.
YANG WG,XIAO YL,CHEN X,ZENG YY,XIAO L.Analysis of the curative effect of small incision nucleus fragmentation non-phacoemulsification cataract surgery[J].Med J Southwest Natl Def,2012,22(3):281-282.
[4] 王炜,赵广华,左元新,赵丹丹,孙利.小切口非超声乳化囊袋内手法劈核术在硬核性白内障中的应用[J].眼科新进展,2011,31(1):52-54.
WANG W,ZHAO GH,ZUO YX,ZHAO DD,SUN L.Application of small-incision non-phacoemulsification intracapsular nucleus chopping technique for hard nucleus cataract[J].Rec Adv Ophthalmol,2011,31(1):52-54.
[5] EMERY JM,LITTLE JH.Phacoemulsification and aspiration of cataract[M].London:Mosby,1993:323.
[6] 陈昌海,杨漪,黄景云,王昕华.超声乳化术治疗对白内障患者角膜内皮细胞及泪液炎性指标的影响[J].海南医学院学报,2016,22(2):197-198,202.
CHEN CH,YANG Y,HUANG JY,WANG QH.Influence of phacoemulsification on corneal endothelial cells and tear inflammatory indexes of patients with cataract[J].J Hainan Med Univ,2016,22(2):197-198,202.
[7] GOKTAS A,GUMUS K,MIRZA GE,CROCKETT C,KARAKUCUK S.Corneal endothelial characteristics and central corneal thickness in a population of Turkish cataract patients[J].Eye Contact Lens,2012,38(3):142-145.
[8] DELSHAD S,CHUN JM.Corneal endothelial cell density and morphology in low and moderate myopic Chinese eyes[J].Int J Ophthalmol,2013,6(4):467-470.
[9] LEEM HS,LEE KJ,SHIN KC.Central corneal thickness and corneal endothelial cell changes caused by contact lens use in diabetic patients[J].Yonsei Med J,2011,52(2):322-325.
[10] 刘洪,刘忠兰,吴波,陈中山,李镭.超声乳化拦截劈核联合手法娩核在硬核性白内障手术中的应用[J].四川医学,2016,37(9):1005-1007.
LIU H,LIU ZL,WU B,CHEN ZS,LI L.Phacoemulsification with Chop Technique Applied to Intercept Nuclear Delivery inHard Cataract Surgery[J].Sichuan Med J,2016,37(9):1005-1007.
[11] 李晓鹏,高建伟,王爽,李彦,刘静.白内障超声乳化联合人工晶状体植入术治疗原发性闭角型青光眼合并白内障临床疗效观察[J].新乡医学院学报,2015,32(2):169-170,174.
LI XP,GAO JW,WANG S,LI Y,LIU J.Clinical effect of phacoemulsification combined with intraocular lens implantation in management of primary angle-closure glaucoma with cataract[J].J Xinxiang Med Univ,2015,32(2):169-170,174.
[12] 朱大强,张霞.超声乳化劈核技术在硬核性白内障手术中的应用[J].眼外伤职业眼病杂志,2010,32(6):464-465.
ZHU DQ,ZHANG X.Application of phacoemulsification chop nucleus in hard nucleus cataract surgery[J].Chin J Ocul Trauma Occup Eye Dis,2010,32(6):464-465.
[13] PARK J H,LEE S M,KWON J W,KIM MK,HYON JY,WEE WR,et al.Ultrasound energy in phacoemulsification:a comparative analysis of phaco-chop and stop-and-chop techniques according to the degree of nuclear density[J].Ophthalmic Surg Lasers Imaging,2010,41(2):236-241.
[14] THAKUR S K,DAN A,SINGH M.Endothelial cell loss after small-ncision cataract surgery[J].Nepal J Ophthalmol,2011,3(2):177-180.
[15] 王静,莫纯坚.1.8 mm同轴微切口超声乳化白内障吸出术对角膜内皮细胞的损伤及修复研究[J].眼科新进展,2015,35(4):377-380.
WANG J,MO CJ.Study on the damage and repair of corneal endothelial cells by 1.8 mm coaxial micro-incision phacoemulsification[J].Rec Adv Ophthalmol,2015,35(4):377-380.

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备注/Memo

备注/Memo:
辽宁省自然科学基金项目(编号:2015010320-301)
更新日期/Last Update: 2017-08-02