[1]吴志中,闫博婧,崔卉,等.结晶样视网膜变性患者五种血清离子的异常变化[J].眼科新进展,2016,36(5):439-442.[doi:10.13389/j.cnki.rao.2016.0117]
　WU Zhi-Zhong,YAN Bo-Jing,CUI Hui,et al.Abnormalities of five serum ions in patients with Bietti crystalline dystrophy[J].Recent Advances in Ophthalmology,2016,36(5):439-442.[doi:10.13389/j.cnki.rao.2016.0117]
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结晶样视网膜变性患者五种血清离子的异常变化
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
36卷
期数:
2016年5期
页码:
439-442
栏目:
应用研究
出版日期:
2016-05-05

文章信息/Info

Title:
Abnormalities of five serum ions in patients with Bietti crystalline dystrophy
作者:
吴志中; 闫博婧; 崔卉; 吴秋菊; 崇伟华; 李根林
100730　首都医科大学附属北京同仁医院北京同仁眼科中心北京市眼科学与视觉科学重点实验室
Author(s):
WU Zhi-Zhong;  YAN Bo-Jing ;  CUI Hui; WU Qiu-Ju ;  CHONG Wei-Hua;  LI Gen-Lin
Beijing Tongren Eye Center, Beijing Tongren Hospital,Capital Medical University,Beijing Ophthalmology & Visual Sciences Key Lab,Beijing 100730,China
关键词:
结晶样视网膜变性; 血清浓度; 钾离子; 钙离子; 镁离子; 钠离子; 氯离子
Keywords:
Bietti crystalline dystrophy ;  serum concentration ;  potassium ;  calcium ;  magnesium ;  sodium ;  chloride
DOI:
10.13389/j.cnki.rao.2016.0117
文献标志码:
A
摘要:
目的　分析结晶样视网膜变性（Ｂｉｅｔｔｉｃｒｙｓｔａｌｌｉｎｅｄｙｓｔｒｏｐｈｙ，ＢＣＤ）患者血清中镁、钙、钾、钠及氯离子浓度的变化情况。方法　采用回顾性序列病例研究方法，选取临床诊断为ＢＣＤ患者５０例纳入ＢＣＤ组，另选取９９位正常人作为正常对照组，按盲法由专业技术人员完成血清离子浓度检测，并分别行ＢＣＤ组和正常对照组比较。结果　ＢＣＤ组患者血清中，钙离子和钾离子浓度分别为（２．３２３±０．０９２）ｍｍｏｌ·Ｌ－１和（４．１２３±０．３５５）ｍｍｏｌ·Ｌ－１，与正常对照组相比均显著升高（ｔ＝－４．２６６，Ｐ＝０．０００；ｔ＝－４．０８１，Ｐ＝０．０００）；镁离子浓度为（０．８４５±０．０５２）ｍｍｏｌ·Ｌ－１，与正常对照组血清中镁离子浓度（０．８７４±０．０７６）ｍｍｏｌ·Ｌ－１相比显著下降（ｔ＝２．７６７，Ｐ＝０，００６）；钠和氯两种离子血清浓度与正常对照组相比差异均无统计学意义（均为Ｐ＞０．０５）。结论　ＢＣＤ患者血清中钙离子和钾离子浓度升高，镁离子浓度降低，其可能与ＢＣＤ的发病有关。
Abstract:
Objective To study the concentration changes of serum magnesium , calcium , potassium , sodium and chloride ions in patients with Bietti crystalline dystrophy( BCD). Methods Based on the retrospective study and the simple size in the statistics,50 patients with BCD and 99 normal people were taken serum ions test by professionals in hospital according to single blind study. Data were analyzed statistically between BCD and normal group. Results In the clinical serum ions test of BCD group , the concentration of calcium and potassium were ( 2. 323 + 0. 092) mmol . L -l and ( 4. 123 + 0. 355 ) mmol . L ’ I , respectively , which were sigruficantly higher than those of normal group ( t = - 4. 266 ,P = 0. 000 ; t = - 4. 081 ,P = 0. 000 ) , but the concentration of magnesium was (0. 845 +0. 052) mmol . L -l .which was significantly lower than the normal group ( t = 2. 767 ,P = 0. 006) . There was no sigruficant difference in remainder two serum ions concentration between BCD and normal group ( all P > 0. 05 ) . Conclusion In patients with BCD .the concentration of calcium and potassium increases . and the concentration of magnesium decreases , which are probably related with the occurrence of BCD.

相似文献/References:

[1]何婷,李孟达,殷晓贝,等.结晶样视网膜变性患者脉络膜和视网膜血流的异常变化[J].眼科新进展,2014,34(6):542.[doi:10.13389/j.cnki.rao.2014.0148]
[2]代贺华,张芷萌,王蕾,等.Usher综合征患者血清离子浓度的变化[J].眼科新进展,2019,39(7):645.[doi:10.13389/j.cnki.rao.2019.0148]
　DAI He-Hua,ZHANG Zhi-Meng,WANG Lei,et al.Changes in the serum ion concentration in patients with Usher syndrome[J].Recent Advances in Ophthalmology,2019,39(5):645.[doi:10.13389/j.cnki.rao.2019.0148]

备注/Memo

备注/Memo:
国家自然科学基金资助（编号：８１２７１０４６）；北京市教育委员会科技发展计划重点项目（编号：ＫＺ２０１５１００２５０２５）
更新日期/Last Update: 2016-05-04