[1]卜战云,郑嵩山,李晓华,等. 原发性泪腺上皮性肿瘤患者97例诊治分析[J].眼科新进展,2015,35(8):751-753.[doi:10.13389/j.cnki.rao.2015.0206]
　BU Zhan-Yun,ZHENG Song-Shan,LI Xiao-Hua,et al. Diagnostic and therapeutical analysis of 97 cases of primary lacrimal gland epithelial tumor[J].Recent Advances in Ophthalmology,2015,35(8):751-753.[doi:10.13389/j.cnki.rao.2015.0206]
点击复制

 原发性泪腺上皮性肿瘤患者97例诊治分析
分享到：

《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
35卷
期数:
2015年8期
页码:
751-753
栏目:
应用研究
出版日期:
2015-08-05

文章信息/Info

Title:
 Diagnostic and therapeutical analysis of 97 cases of primary lacrimal gland epithelial tumor
作者:
 卜战云; 郑嵩山; 李晓华; 柴昌
 450003　河南省郑州市，河南省立眼科医院河南省眼科研究所
Author(s):
 BU Zhan-Yun; ZHENG Song-Shan ;  LI Xiao-Hua; CHAI Chang
 Henan Eye Hospital, Henan Eye Institute , Zhengzhou 450003 , Henan Province . China
关键词:
 ; 泪腺; 上皮性肿瘤; 多形性腺瘤; 腺样囊性癌; 多形性腺癌
Keywords:
 ; lacrimal gland ;  epithelial tumor ;  pleomorphic adenoma ;  adenoid cystic carcinoma ;  pleomorphic adenocarcinoma
DOI:
10.13389/j.cnki.rao.2015.0206
文献标志码:
A
摘要:
 目的　探讨泪腺上皮性肿瘤的临床表现、影像学特征、诊断方法及治疗原则。方法　对２００３年１月至２０１４年１０月在河南省眼科研究所就诊的９７例泪腺上皮性肿瘤的临床表现、影像学检查、治疗方法、术后视力、及随访情况等临床资料进行回顾性分析。采用前路开眶１１例，常规外侧开眶１９例，改良“Ｓ”形皮肤切口并外侧开眶６７例。结果　９７例泪腺上皮性肿瘤中，泪腺多行性腺瘤６５例（６７．０１％），腺样囊性癌１６例（１６．４９％），多形性腺癌１２例（１２．３７％），腺癌２例（２．０６％），黏液表皮样癌１例（１．０３％），肌上皮瘤１例（１．０３％）。术后视力提高３７例，无变化５４例，下降６例。１３例出现眼球内陷，早期上睑下垂１１例，４例出现外展运动受限、水平复视。术后６个月随访：上睑下垂４例；１例出现永久性外展不足、水平复视。结论　泪腺上皮性肿瘤具有典型的临床表现和特征性的影像学改变，术前通过准确的定位来选择适宜的手术进路，可顺利并完整地切除肿瘤，避免肿瘤复发和出现严重并发症。
Abstract:
 Objective To investigate the clinical manifestations . characteristics of iconography , diagnostic methods and therapeutic principles of primary lacrimal gland epithelial tumor. Methods The clinical data on clinical marufestations . examinations of iconography ,therapeutic methods , follow-up and so on of 97 cases of primary lacrimal gland epithelial tumor in Henan Eye Institute from January 2003 to October 2014 were analyzed retrospectively. Anterior orbitotomy was adopted in 11 cases ,routine lateral orbitotomy for 19 cases , improved " S" shape skin incision and lateral orbitotomy for 67 cases. Results In 97 cases of primary lacrimal gland epithelial tumor, there were 65 cases ( 67. 01% ) for benign pleomorphic adenoma of lacrimal gland, 16 cases ( 16. 4g% ) for adenoid cystic carcinoma , 12 cases( 12. 37% ) for pleomorphic adenocarcinoma.2 cases(2. 06% ) for glandular cancer, I case ( 1. 03% ) each for mucoepidermoid carcinoma and myoepithelioma. Postoperative vision was improved in 37 cases. not changed in 54 cases , descented in 6 cases. Endophthalmos was found in 13 cases , early ptosis in 11 cases , abduction exercise limitation and horizontal diplopia in 4 cases. Follow up for 6 months after operation : ptosis appeared in 4 cases ,permanent abduction insufficient and diplopia appeared in I case. Conclrisions There are classic clinical manifestations and distinctive iconography changes in lacrimal gland epithelial tumor. By accurate localization before operation and selecting the proper surgical approach , the tumor can be excised successfully and completely, and the recurrence of tumor and severe complication also can be avoided.

相似文献/References:

[1]刘平 苏胜. 白内障蛋白质组学研究的现状及未来研究方向[J].眼科新进展,2014,34(1):001.
[2]杨宝娣 宋艳萍 陈中山 丁琴. 微脉冲半导体激光对兔视网膜色素上皮细胞阈值下光凝的光生物调制效应[J].眼科新进展,2014,34(1):005.
[3]赖伟霞 梁皓 谭少健 李霞 邹文进 蒋林志. 钙调素在正常人及不同年龄白内障患者晶状体上皮细胞中的表达[J].眼科新进展,2014,34(1):010.
[4]郑燕林 刘聪慧 沙菽. 水蛭提取液对体外培养RF/6A的细胞液中MMP-2、IV型胶原含量的影响[J].眼科新进展,2014,34(1):013.
[5]周琨 高晓唯 蔡岩 李文静 胡裕坤 田丽丽 付燕. CCR7基因修饰的未成熟树突状细胞在大鼠高危角膜移植免疫排斥反应中的作用[J].眼科新进展,2014,34(1):017.
[6]高伟 程燕 吴洁 王亮 赵帅. 肉毒杆菌B诱导大鼠干眼模型中泪腺Lacritin蛋白表达的研究[J].眼科新进展,2014,34(1):021.
[7]赵宁 张瑞君 刘磊 李佳 刘宁宁. PTEN基因对兔晶状体上皮细胞增殖抑制作用的实验研究[J].眼科新进展,2014,34(1):025.
[8]陈雪 李海平 张培 曹安民. 小胶质细胞在视网膜母细胞瘤中的活化及分布研究[J].眼科新进展,2014,34(1):029.
[9]李琴 谢婷玉 陈雪艺 王清 郭乔茜 具尔提·哈第尔. 臭氧灌肠改善糖尿病大鼠的视网膜电图表现[J].眼科新进展,2014,34(1):034.
[10]蔡晶晶 孟倩丽 郭海科 张良 李东风 崔颖. 血红素加氧酶-1在糖尿病视网膜病变患者外周血单个核细胞中的表达[J].眼科新进展,2014,34(1):037.
[11]李静,葛心,马建民. 泪腺良性淋巴上皮病变免疫组织化学研究[J].眼科新进展,2015,35(5):439.[doi:10.13389/j.cnki.rao.2015.0119]
　LI Jing,GE Xin,MA Jian-Min. Immunohistochemical research on benign lymphoepithelial lesion of lacrimal gland[J].Recent Advances in Ophthalmology,2015,35(8):439.[doi:10.13389/j.cnki.rao.2015.0119]

更新日期/Last Update: 2015-07-31