[1]赵晓彬,张海芳,董素婷. 年龄相关性白内障角膜前表面高阶像差分析[J].眼科新进展,2015,35(4):359-361.[doi:10.13389/j.cnki.rao.2015.0096]
　ZHAO Xiao-Bin,ZHANG Hai-Fang,DONG Su-Ting. Analysis of anterior corneal higher-order aberrations in age-related cataract[J].Recent Advances in Ophthalmology,2015,35(4):359-361.[doi:10.13389/j.cnki.rao.2015.0096]
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 年龄相关性白内障角膜前表面高阶像差分析
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
35卷
期数:
2015年4期
页码:
359-361
栏目:
应用研究
出版日期:
2015-04-05

文章信息/Info

Title:
 Analysis of anterior corneal higher-order aberrations in age-related cataract
作者:
 赵晓彬; 张海芳; 董素婷
 050051 河北省石家庄市，河北省人民医院眼科
Author(s):
 ZHAO Xiao-Bin ; ZHANG Hai-Fang ;  DONG Su-Ting
 Department of Ophthalmology , People ’ s Hospital of Hebei Province , Shijiazhuang 050051 , Hebei Province , China
关键词:
 ; 年龄相关性白内障; 高阶像差; 角膜前表面
Keywords:
 ; age-related cataract ;  higher-order aberration;  anterior cornea
DOI:
10.13389/j.cnki.rao.2015.0096
文献标志码:
A
摘要:
 目的　观察年龄相关性白内障患者角膜前表面高阶像差的大小及其与年龄的关系。方法　对２０１３年１月至１２月在我院行手术治疗的年龄相关性白内障患者２００例（２００眼）术前相关资料进行回顾性分析，根据年龄将患者分为４组：组１：≥５０～５９岁（３４例）；组２：≥６０～６９岁（５８例）；组３：≥７０～７９岁（６６例）；组４：≥８０岁（４２例）。采用ｉＴｒａｃｅ视觉功能分析仪测量角膜前表面６ｍｍ直径内总高阶像差、彗差、三叶草、球差，采用方差分析和Ｐｅａｒｓｏｎ相关分析对获得的数据进行统计。结果　２００例（２００眼）患者角膜前表面总高阶像差、彗差、三叶草、球差值分别为０．２６８～０．８９７（０．５３４±０.１２２）μｍ、０．０２４～０．７２６（０．２８７±０．１１９）μｍ、０．０１９～０．６８１（０．２７６±０．１２１）μｍ和０．０５４～０．５５２（０．２６８±０．０８３）μｍ。４组患者角膜前表面总高阶像差、彗差、三叶草值随年龄的增大而增大，差异有统计学意义（Ｐ＜０．００１），且两两比较差异均有统计学意义（均为Ｐ＜０．０５）；４组患者角膜前表面球差差异无统计学意义（Ｐ＝０．２９７）。４组患者的球镜值、角膜散光、角膜Ｑ值差异均无统计学意义（均为Ｐ＞０．０５）。角膜前表面总高阶像差、彗差、三叶草值与年龄呈正相关（ｒ＝０．２７４、０．２０３、０．１８８，均为Ｐ＜０．００１），但球差与年龄无明显相关性（ｒ＝０．０３４，Ｐ＝０．７１５）。结论　年龄相关性白内障患者角膜前表面高阶像差在不同个体间差异很大，总高阶像差、彗差、三叶草像差随年龄增长逐渐增大，球差随年龄增长无明显变化。
Abstract:
 Objective To investigate the distribution of anterior corneal higher-order aberrations ( HOA) in age-related cataract and their correlations with age. Methods Retrospective study. Two hundred patients with age-related cataract in our hospital from January 2013 to December 2013 were divided into four groups according to their age: group I (50 -59 years old, 34 cases) , group 2 (；60 - 69 years old. 58 cases) , group 3 (≥70 - 79 years old. 66 cases) , group 4 (≥ 80 years old, 42 cases). The total HOA, coma aberration . trefoil aberration and spherical aberration in the central 6-mm zone of the anterior cornea were measured with iTrace wavefront analyzer. ANOVA and Pearson analysis were used to analyze the data. Results For all the cases. the total HOA, coma aberration, trefoil aberration and spherical aberration were 0. 268 - 0. 897 ( 0. 534 + 0. 122 ) Vm, 0. 024 - 0. 726 ( 0. 287 + 0. 122 ) ym, 0. 019 - 0. 681 (0. 276 + 0. 121 ) ym and 0. 054 - 0. 552 ( 0. 268 + 0. 083 ) ym, respectively. The total HOA. coma aberration. trefoil aberration in four groups were increased with the increase of age (P < 0. 001) , and there were statistical differences between each two groups ( all P < 0. 05 ) . There was no statistical difference in spherical aberration among four groups (P = 0. 297) . There was no statistical difference in spherical value , corneal astigmatism and Q value among four groups ( all P > 0. 05 ) . The positive correlations were found between age and total HOA. coma aberration and trefoil aberration ( r= 0. 274 . 0. 203 , 0. 188 ; all P <0. 001). However, no correlation was found between age and spherical aberration ( r = 0. 034 , P = 0. 715 ) . Conclusion Anterior corneal higher-order aberrations in people with age-related cataract have greatly differences among subjects. With the increase of age, total HOA. coma aberration and trefoil aberration increased, whereas spherical aberration do not change.

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备注/Memo

备注/Memo:
 河北省卫生厅科研项目（编号：２０１２０２１６）
更新日期/Last Update: 2015-03-31