[1]罗丹,金明.脉络膜新生血管抑制剂最新研究进展[J].眼科新进展,2017,37(3):285-288.[doi:10.13389/j.cnki.rao.2017.0072]
　LUO Dan,JIN Ming.Research advances in inhibitors for choroid neovascularization[J].Recent Advances in Ophthalmology,2017,37(3):285-288.[doi:10.13389/j.cnki.rao.2017.0072]
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脉络膜新生血管抑制剂最新研究进展/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年3期
页码:
285-288
栏目:
文献综述
出版日期:
2017-03-05

文章信息/Info

Title:
Research advances in inhibitors for choroid neovascularization
作者:
罗丹; 金明
100029　北京市，中日友好医院眼科
Author(s):
LUO Dan; JIN Ming
Department of Ophthalmology，China-Japan Friendship Hospital，Beijing 100029，China
关键词:
脉络膜新生血管; 血管内皮生长因子; 血管内皮生长因子受体; 氧化还原; 炎症
Keywords:
choroid neovascularization; vascular endothelial growth factor; vascular endothelial growth factor receptor; redox; inflammation
分类号:
R773.4
DOI:
10.13389/j.cnki.rao.2017.0072
文献标志码:
A
摘要:
脉络膜新生血管是脉络膜血管病理性增生表现，易伴发出血及渗出，是致盲的主要因素之一。目前针对脉络膜新生血管的治疗成为了研究热点，并且在血管内皮生长因子及其受体抑制剂、内源性血管生成因子抑制剂、氧化还原和炎症反应相关因子抑制剂等研究上取得了一定进展，有关此病的中药治疗也取得相应成就。本文就脉络膜新生血管抑制剂最新研究进展展开综述。
Abstract:
Choroid neovascularization (CNV) is pathological proliferation of choroid vascular,accompanying with bleeding and leakage,is one of the major factors caused blindness,so CNV inhibitors have become a research hotspot.At present,researches on inhibitors of vascular endothelial growth factors and their receptors,endogenous angiogenesis factors,redox and inflammatory response related factors,etc,have achieved certain progresses.In addition,as drugs with multiple targets for treatment,many Chinese herbs also show inhibition effect on CNV.This article reviews the research advances in inhibitors for CNV.

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备注/Memo

备注/Memo:
国家自然科学基金资助（编号：81373693）
更新日期/Last Update: 2017-04-01