[1]王文婷,乔璐,陈乐民,等.不同后光学区直径角膜塑形镜控制近视效果的Meta分析[J].眼科新进展,2024,44(4):311-316.[doi:10.13389/j.cnki.rao.2024.0061]
　WANG Wenting,QIAO Lu,CHEN Lemin,et al.Meta-analysis of the myopia control effect of orthokeratology lenses with different back optical zone diameters[J].Recent Advances in Ophthalmology,2024,44(4):311-316.[doi:10.13389/j.cnki.rao.2024.0061]
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不同后光学区直径角膜塑形镜控制近视效果的Meta分析/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
44卷
期数:
2024年4期
页码:
311-316
栏目:
应用研究
出版日期:
2024-04-05

文章信息/Info

Title:
Meta-analysis of the myopia control effect of orthokeratology lenses with different back optical zone diameters
作者:
王文婷; 乔璐; 陈乐民; 彭绍民
230031　安徽省合肥市，安徽医科大学附属爱尔眼科医院（王文婷，彭绍民）；750000　宁夏回族自治区银川市，宁夏爱尔眼科医院（王文婷，乔璐，陈乐民）
Author(s):
WANG Wenting1; 2; QIAO Lu2; CHEN Lemin2; PENG Shaomin1
1.Aier Eye Hospital Affiliated to Anhui Medical University,Hefei 230031,Anhui Province,China
2.Ningxia Aier Eye Hospital,Yinchuan 750000,Ningxia Hui Autonomous Region,China
关键词:
角膜塑形镜; 近视; 后光学区直径; Meta分析
Keywords:
orthokeratology lens;  myopia;  back optic zone diameter;  meta-analysis
分类号:
R778.1
DOI:
10.13389/j.cnki.rao.2024.0061
文献标志码:
A
摘要:
目的　系统评价近视患者配戴不同后光学区直径角膜塑形镜后眼轴长度及治疗区直径的变化。
方法　计算机检索PubMed、Embase、the Cochrane Library、Web of Science、万方医学网和中国知网（CNKI）等数据库，文种限中英文，收集配戴不同后光学区直径角膜塑形镜的随机对照试验或对照试验。由2位研究员经过文献筛选和相关数据资料的提取及方法学质量评价之后，使用RevMan 5.3软件进行Meta分析。所纳入研究均以配戴常规后光学区直径的角膜塑形镜为对照组，配戴后光学区直径减小的角膜塑形镜为试验组。
结果　最终纳入8篇文献，共437例459眼近视患者。Meta分析结果显示，配戴角膜塑形镜6个月及 12个月后，试验组眼轴长度变化均明显小于对照组（6个月:MD=-0.09，95%CI:-0.10~-0.07，Z=10.50，P<0.05；12个月:MD=-0.11，95%CI：-0.13~-0.09,Z=12.19，P<0.05）；试验组和对照组在配戴角膜塑形镜后不同时间点测定的治疗区直径大小变化差异具有统计学意义（MD=-0.82,95%CI:-1.04~-0.59,Z=7.03，P<0.05）。
结论　后光学区直径减小的角膜塑形镜能够有效延缓近视患者眼轴长度的增长，但长期疗效仍需进一步研究证实。
Abstract:
Objective　To systematically evaluate the changes in axial length and treatment zone diameter among myopic patients wearing orthokeratology lenses with different back optic zone diameters.
Methods　A comprehensive literature search was conducted on PubMed, Embase, the Cochrane Library, Web of Science, Wangfang Med Online and CNKI databases in both Chinese and English to identify randomized controlled trials or controlled trials investigating orthokeratology lenses with varying back optical zone diameters. The literature was thoroughly reviewed by two researchers, who extracted relevant data and conducted a methodological quality evaluation. Finally, meta-analysis was performed using RevMan 5.3 software. In all the included studies, orthokeratology lenses with a conventional back optic zone diameter were taken as the control group, while orthokeratology lenses with a reduced back optic zone diameter were utilized as the experimental group.
Results　Eight studies involving 437 patients (459 eyes) with myopia were included. The results of meta-analysis showed that the axial length changes in the experimental group were significantly lower than those of the control group after wearing orthokeratology lenses for 6 months and 12 months (6 months: MD=-0.09, 95% CI: -0.10 to -0.07, Z=10.50, P<0.05; 12 months: MD=-0.11, 95% CI: -0.13 to -0.09, Z=12.19, P<0.05); significant differences in treatment zone diameter were observed between the experimental and control groups at various time points following orthokeratology lens wearing (MD=-0.82, 95% CI: -1.04 to -0.59, Z=7.03, P<0.05).
Conclusion　Orthokeratology lenses designed with smaller back optical zone diameters can effectively delay axial length growth in myopic patients, but their long-term efficacy needs to be confirmed.

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备注/Memo

备注/Memo:
银川市科技计划项目(编号：2021-SF-19)；宁夏回族自治区卫生健康委员会系统科研课题项目(编号：2022-NWKY-079)
更新日期/Last Update: 2024-04-05