[1]刘杨,李梦迪,李丽华,等.高度近视儿童青少年配戴多焦点软性接触镜延缓近视进展的有效性研究[J].眼科新进展,2023,43(5):388-392.[doi:10.13389/j.cnki.rao.2023.0078]
 LIU Yang,LI Mengdi,LI Lihua,et al.Effectiveness of multifocal soft contact lenses in slowing myopia progression of adolescents with high myopia[J].Recent Advances in Ophthalmology,2023,43(5):388-392.[doi:10.13389/j.cnki.rao.2023.0078]
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高度近视儿童青少年配戴多焦点软性接触镜延缓近视进展的有效性研究/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
43卷
期数:
2023年5期
页码:
388-392
栏目:
应用研究
出版日期:
2023-05-05

文章信息/Info

Title:
Effectiveness of multifocal soft contact lenses in slowing myopia progression of adolescents with high myopia
作者:
刘杨李梦迪李丽华陈晓琴杨晓艳李轩
300000 天津市,天津医科大学眼科临床学院(刘杨,李轩);300000 天津市,天津市眼科医院视光中心(李梦迪,李丽华,陈晓琴,杨晓艳)
Author(s):
LIU Yang1LI Mengdi2LI Lihua2CHEN Xiaoqin2YANG Xiaoyan2LI Xuan1
1.The Clinical School of Ophthalmology of Tianjin Medical University,Tianjin 300000,China
2.Tianjin Eye Hospital Optometric Center,Tianjin 300000,China
关键词:
高度近视多焦点软性接触镜近视防控
Keywords:
high myopia multifocal soft contact lens myopia control
分类号:
R778
DOI:
10.13389/j.cnki.rao.2023.0078
文献标志码:
A
摘要:
目的 评估高度近视儿童青少年配戴多焦点软性亲水性接触镜延缓近视进展的有效性。
方法 回顾性研究。纳入2018年11月到2020年2月于天津市眼科医院视光中心配戴多焦点软性亲水性接触镜的近视儿童青少年36例和配戴单光框架眼镜者36例(均选取右眼),年龄为8~15岁,等效球镜度(SE)为-5.00~-10.00 D。记录患者年龄、性别等信息,收集患者基线及戴镜1年后的主觉屈光度、眼轴长度等指标。采用独立样本t检验分析两组患者基线与1年后的SE变化量及眼轴长度变化量,采用多元线性回归分析影响屈光度及眼轴长度变化的因素,二元Logistic回归分析影响进展性近视发展的因素。
结果 配戴多焦点软性亲水性接触镜组患儿与单光框架眼镜组患儿相比,两组间1年的SE变化量及眼轴长度变化量差异均有统计学意义(t=5.407,P<0.001;t=-2.763,P=0.007)。多元线性回归分析发现,SE进展的主要影响因素是戴镜组别和基线眼轴长度,回归方程:SE=3.982+0.458×戴镜组别-0.138×基线眼轴长度(R2=0.375,调整R2=0.357);眼轴变化主要影响因素为戴镜组别,回归方程:AL=0.116+0.120×戴镜组别(R2=0.097,调整R2=0.097)。对于是否成为进展性近视儿童来说,配戴单光框架眼镜组的风险是多焦点软镜的12.571倍。
结论 高度近视儿童青少年配戴多焦点软性接触镜能延缓近视进展(65.4%)及眼轴生长(33.3%)。
Abstract:
Objective To evaluate the effectiveness of multifocal soft hydrophilic contact lenses in slowing the progression of high myopia.
Methods A retrospective study was conducted. A total of 36 myopia adolescents who were fitted with multifocal soft hydrophilic contact lenses (right eye) and 36 adolescents who were fitted with single-vision lenses (right eye) in the Optometric Center, Tianjin Eye Hospital from November 2018 to February 2020 were included. These participants were 8-15 years old and had a spherical equivalent (SE) from -5.00 D to -10.00 D. Age, gender, subjective refraction and axial length (AL) at baseline and 1 year after lens wearing were collected. Independent sample t-test was used to analyze the changes in SE and AL of patients in the two groups at baseline and 1 year after lens wearing, multiple regression analysis was used to analyze the factors influencing diopter and AL changes, and binary logistic regression analysis was carried out to explore the factors affecting progressive myopia.
Results There were significant differences in the SE and AL changes between adolescents wearing multifocal soft contact lens and adolescents wearing single-vision lenses (t=5.407, P<0.001; t=-2.763, P=0.007). Multiple linear regression analysis demonstrated that the main influencing factors on SE were category of lenses and AL at baseline, and the regression equation was: SE=3.982+0.458×category of lenses-0.138×AL at baseline (R2=0.375, adjusted R2=0.357). The main influencing factor on AL was category of lenses, and the regression equation was: AL=0.116+0.120×category of lenses (R2=0.097, adjusted R2=0.097). The risk of progressive myopia in adolescents wearing single-vision lenses was 12.571 times of adolescents wearing multifocal soft lenses.
Conclusion Multifocal soft contact lens has a good performance in slowing the degradation of diopter (65.4%) and AL (33.3%) for children with high myopia.

参考文献/References:

[1] HOLDEN B A,FRICKE T R,WILSON D A,JONG M,NAIDOO K S,SANKARIDURG P,et al.Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050[J].Ophthalmology,2016,123( 5):1036.
[2] 重视高度近视防控的专家共识(2017)[J].中华眼视光学与视觉科学杂志,2017,19(7):385-389.
Prevention and control of high myopia(2017) [J].Chin J Optom Opthalmol Vis Sci,2017,19(7):385-389.
[3] 童彦会,刘慧彬,王政和,杨忠平,徐荣彬,杨招庚,等.中国2005-2014年7~18岁汉族儿童青少年近视现状和增长速度趋势分析[J].中华流行病学杂志,2017,38(5):583-587.
DONG Y H,LIU H B,WANG Z H,YANG Z P,XU R B,YANG Z G,et al.Prevalence of myopia and increase trend in children and adolescents aged 7-18 years in Han ethnic group in China,2005-2014[J].Chin J Epidemiol,2017,38(5):583-587.
[4] SMITH E L.Prentice Award Lecture 2010:a case for peripheral optical treatment strategies for myopia[J].Optom Vis Sci,2011,88(9):1029-1044.
[5] SMITH E L,KEE C S,RAMAMIRTHAM R,QIAO G Y,HUNG L F.Peripheral vision can influence eye growth and refractive development in infant monkeys[J].Invest Ophthalmol Vis Sci,2005,46(11):3965-3972.
[6] WILDSOET C,WALLMAN J.Choroidal and scleral mechanisms of compensation for spectacle lenses in chicks[J].Vision Res,1995,35(9):1175-1194.
[7] JR J,NORTON T T.The susceptible period for deprivation-induced myopia in tree shrew[J].Vision Res,1998,38(22):3505-3515.
[8] HUANG Y,LI X,DING C,CHEN Y,MAO X,CHEN H,BAO J.Comparison of peripheral refraction and higher-order aberrations between orthokeratology and multifocal soft contact lens designed with highly addition[J].Graefes Arch Clin Exp Ophthalmol,2022,260(5):1755-1762.
[9] 郭寅,田飞飞,吴敏,冯祎,唐萍,吕燕云.周边离焦设计框架眼镜对学龄儿童近视进展的影响:四年回顾分析[J].中华眼视光学与视觉科学杂志,2021,23(4):267-271.
GUO Y,TIAN F F,WU M,FENG Y,TANG P,LU Y Y.Myopia progression in children wearing peripheral defocus modifying lenses:four years of retrospective analysis[J].Chin J Optom Ophthalmol Vis Sci,2021,23(4):267-271.
[10] 吴海燕,胡琦.视网膜周边离焦学说的应用进展[J].中国斜视与小儿眼科杂志,2020,28(4):40-42.
WU H Y,HU Q.The application progress of peripheral retinal defocus theory[J].Chin J Strabismus Pediatr Ophthalmol,2020,28(4):40-42.
[11] SANKARIDURG P,BAKARAJU R C,NADUVILATH T,CHEN X,WENG R,TILIA D,et al.Myopia control with novel central and peripheral plus contact lenses and extended depth of focus contact lenses:2 year results from a randomised clinical trial[J].Ophthalmic and Physiological Optics,2019.39(4):297-307.
[12] 熊雪薇.近视的药物治疗和光学矫正研究新进展[J].疑难病杂志,2019,18(7):752-756.
XIONG X W.Recent advances in drug therapy and optical correction of myopia[J].Chin J Diffic Compl Cas,2019,18(7):752-756.
[13] 褚慧慧,赵寅政,张俊娜,刘曦,余继峰.儿童近视早期不同干预方法的疗效分析[J].中国斜视与小儿眼科杂志,2022,30(1):5-7.
CHU H H,ZHAO Y Z,ZHANF J N,LIU X,YU J F.Clinical analysis of different intervention to control early myopia in children[J].Chin J Strabismus Pediatr Ophthalmol,2022,30(1):5-7.
[14] 陈晓琴,刘金丽,张姝贤,李丽华.青少年近视患者配戴角膜塑形镜5年的有效性及安全性[J].眼科新进展,2021,41(3):236-239.
CHEN X Q,LIU J L,ZHANg S X,LI L H.Efficacy and security of orthokeratology lens on myopia progression in teenager for 5 years[J].Rec Adv Opthalmol,2021,41(3):236-239.
[15] HIRAOKA T.Myopia Control With Orthokeratology:a review[J].Eye Contact Lens,2022,48(3):100-104.
[16] HE X,ZHAO R,SANKARIDURG P,ZHU J,NADUVILATH T,MA Y,et al.Design and methodology of the Shanghai child and adolescent large-scale eye study(SCALE)[J].Clin Exp Ophthalmol,2018,46(4):329-338.
[17] WALLINE J J,GREINER K L,MCVEY M E,JONES L A.Multifocal contact lens myopia control[J].Optom Vis Sci,2013,90(11):1207-1214.
[18] VALLE A M,BLAZQUE V,GROS O J,INFANTE M,GULEBRAS A,VERDEJO A,et al.Efficacy and safety of a soft contact lens to control myopia progression[J].Clin Exp Optom,2020,104(1):14-21.
[19] CHARMAN W N,RADHAKRISHNAN H.Peripheral refraction and the development of refractive error:a review[J].Ophthalmic Physiol Opt,2010,30(4):321-338.
[20] BEASLEY I G,DAVIES L N,LOGAN N S.The effect of peripheral defocus on axial growth and modulation of refractive error in hyperopes[J].Ophthalmic Physiol Opt,2022,42(3):534-544.
[21] BENNETT E S.Bifocal and multifocal contact lenses-science direct[J].Contact Lenses,2019:265-288.
[22] 陈君虹,陈思萍,潘雅丽,朱欣欣,侯立杰.多焦点角膜接触镜配戴后角膜屈光力的变化及其与眼轴增长的相关性[J].中华眼视光学与视觉科学杂志,2021,23(6):427-433.
CHEN J H,CHEN S P,PAN Y L,ZHU X X,HOU L J.Correaltion between axial length growth and the relative corneal power shift after using multifocal contact lenses[J].Chin J Optom Ophthalmol Vis Sci,2021,23(6):427-433.
[23] RUIZ P A,PEREZ S B,VALLS I,PRIETO G F L,GUTIERREZ OR,VILLA C C.MiSight Assessment Study Spain(MASS):a 2-year randomized clinical trial[J].Graefes Arch Clin Exp Ophthalmol,2018,256(5):1011-1021.
[24] CHAMBERLAIN P,PEIXOTO S C,LOGAN N S,NGO C,JONES D,YOUNG G.A 3-year randomized clinical trial of MiSight lenses for slowing myopia progression[J].Optom Vis Sci,2019,96(8):556-567.
[25] LEIGHTON D A,TOMLINSON A.Changes in axial length and other dimensions of the eyeball with increasing age[J].Acta Ophthalmol(Copenh),1972,50(6):815-826.
[26] CHAMBERLAIN P,JARA P,ARUMUGAM B,BULLIMORE MA.Axial length targets for myopia control[J].Ophthalmic Physiol Opt,2021,41(3):523-531.
[27] MIN W L,LEE S E,LIM H B,KIN J Y.Longitudinal changes in axial length in high myopia:a 4-year prospective study[J].Br J Ophthalmol,2020,104(5):600-603.

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备注/Memo

备注/Memo:
天津市卫生计生委筛查体系基金支持项目(编号:RC20069)
更新日期/Last Update: 2023-05-05