[1]余海跃,滕娟,朱光.定量分析糖尿病视网膜病变患者视盘周围视网膜和脉络膜血流灌注[J].眼科新进展,2023,43(1):044-46.[doi:10.13389/j.cnki.rao.2023.0009]
　YU Haiyue,TENG Juan,ZHU Guang.Quantitative analysis of peripapillary retinal and choroidal blood perfusion in diabetic retinopathy patients[J].Recent Advances in Ophthalmology,2023,43(1):044-46.[doi:10.13389/j.cnki.rao.2023.0009]
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定量分析糖尿病视网膜病变患者视盘周围视网膜和脉络膜血流灌注/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
43卷
期数:
2023年1期
页码:
044-46
栏目:
应用研究
出版日期:
2023-01-05

文章信息/Info

Title:
Quantitative analysis of peripapillary retinal and choroidal blood perfusion in diabetic retinopathy patients
作者:
余海跃; 滕娟; 朱光
233000　安徽省蚌埠市，蚌埠市第二人民医院眼科
Author(s):
YU Haiyue; TENG Juan; ZHU Guang
Department of Ophthalmology，the Second People’s Hospital of Bengbu，Bengbu 233000，Anhui Province,China
关键词:
糖尿病视网膜病变; 光学相干断层扫描血管成像; 视盘周围视网膜血管密度; 神经纤维层厚度; 脉络膜毛细血管指数; 脉络膜厚度
Keywords:
diabetic retinopathy;  optical coherence tomography angiography;  peripapillary retinal vessel density;  retinal nerve fiber layer;  choroidal vascularity index;  choroidal thickness
分类号:
R774
DOI:
10.13389/j.cnki.rao.2023.0009
文献标志码:
A
摘要:
目的　定量分析不同阶段糖尿病视网膜病变（DR）患者视盘周围视网膜和脉络膜变化。
方法　对90例(90眼)患者进行横断面研究。受试者分为3组：对照组(n=30)、无DR（NDR）组(n=30)和非增生型DR（NPDR）组(n=30)。比较不同组别受试者视盘周围视网膜血流灌注（RP）、视网膜血管密度（RVD）、视网膜神经纤维层厚度（RNFL）、脉络膜血管体积（CVV）、脉络膜血管指数（CVI）、脉络膜厚度（CT）。
结果　与对照组相比，NDR组患者RP［（13.16±0.98）mm2］、RVD［（61.80±5.29）%］、RNFL［（75.41±11.19）μm］均显著降低（均为P<0.05），NPDR组患者RP［（11.70±1.53）mm2］、RVD［（56.92±5.61）%］、RNFL［（68.77±9.61）μm］和CVI（0.16±0.05）均降低（均为P<0.05）。与NDR组相比，NPDR组患者RP、RVD、RNFL和CVI均降低（均为P<0.05）。
结论　NPDR期患者视盘周围视网膜和脉络膜血流已发生变化。扫频OCTA可以用于早期评估DR患者视盘周围视网膜和脉络膜损害。
Abstract:
Objective　To conduct a quantitative analysis of the peripapillary retinal and choroidal blood perfusion changes at different stages of diabetic retinopathy (DR).
Methods　A cross-sectional study was carried out on 90 patients (90 eyes), which were classified into three groups: normal control group (n=30), non-diabetic retinopathy (NDR) group (n=30) and non-proliferative diabetic retinopathy (NPDR) group (n=30). The peripapillary retinal perfusion (RP), retinal vessel density (RVD), retinal nerve fiber layer (RNFL) thickness, choroidal vessel volume, choroidal vascularity index (CVI) and choroidal thickness in the three groups were measured and compared.
Results　Compared with the normal control group, the RP (13.16±0.98) mm2, RVD (61.80±5.29)%and RNFL thickness (75.41±11.19) μm of the NDR group significantly decreased (all P<0.05); the RP (11.70±1.53) mm2, RVD (56.92±5.61)%, RNFL thickness (68.77±9.61) μm and CVI (0.16±0.05) of the NPDR group significantly decreased (all P<0.05). Compared with the NDR group, the RP, RVD, RNFL thickness and CVI of the NPDR group significantly decreased (all P<0.05).
Conclusion　The peripapillary retinal and choroidal blood perfusion has changed in NPDR patinets. The swept source optical coherence tomography angiography can be used for early assessment of peripapillary vascular and nerve injury in DR patients.

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更新日期/Last Update: 2023-01-05